Comparison of granisetron alone and granisetron plus dexamethasone in the prophylaxis of cytotoxic-induced emesis
نویسندگان
چکیده
منابع مشابه
a randomized comparison of granisetron plus dexamethason with granisetron alone for the control of acute chemotherapy-induced emesis and nausea
introduction: chemotherapeutic drugs used to treat cancer may cause nausea and emesis by inducing the release of 5-hydroxytryptamine (5-ht) in the small intestine. blockage of 5-ht 3 receptors in the small intestine by 5-ht 3 receptor antagonists might prevent the nausea and vomiting associated with chemotherapy for cancer. the aim of this study was to compare the efficacy and tolerability of t...
متن کاملOndansetron and Granisetron in the Prophylaxis of Nausea and Emesis Induced by Cisplatin in Dogs
Topal A. , M. Kaya, N. Gül: Ondansetron and Granisetron in the Prophylaxis of Nausea and Emesis Induced by Cisplatin in Dogs. Acta Vet. Brno 2005, 74: 111-116. In the present study, the effects of 5-HT3 receptor antagonist granisetron and ondansetron on the acute phase of cisplatin-induced nausea and emesis were analyzed in dogs. Fifteen healty dogs were used in this study. Cisplatin was admini...
متن کاملThe dose-response relation and cost-effectiveness of granisetron for the prophylaxis of pediatric postoperative emesis.
BACKGROUND Postoperative nausea and vomiting (PONV) may delay discharge from hospital after ambulatory surgery. The antiserotonin agents, ondansetron and granisetron, provide effective prophylaxis against chemotherapy-induced and postoperative nausea and vomiting in adults, but are expensive. We determined the dose-response relation of granisetron and the financial impact of using this drug in ...
متن کاملPrevention of postoperative nausea and vomiting in patients undergoing laparoscopic bariatric surgery--granisetron alone vs granisetron combined with dexamethasone/droperidol.
BACKGROUND AND OBJECTIVES Laparoscopic bariatric surgeries are associated with an appreciably high rate of postoperative nausea and vomiting. This study was designed to compare the effectiveness of granisetron either alone or in combination with droperidol or dexamethasone, for the prevention of post operative nausea and vomiting (PONV) in patients undergoing laparoscopic bariatric surgeries. ...
متن کاملEffective dose of granisetron for preventing postoperative emesis in children.
PURPOSE This study was to identify the minimum effective dose of granisetron, a selective 5-hydroxytryptamine type 3 receptor antagonist, to prevent postoperative vomiting in children who have undergone strabismus repair, tonsillectomy or tonsillectomy with adenoidectomy. METHODS In a randomized, double-blind fashion, 80 healthy children aged 4-10 yr were assigned to receive either placebo (s...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1994
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1994.465